首页 | 官方网站   微博 | 高级检索  
     

急性脑梗死动静脉联合与单纯静脉溶栓治疗的疗效观察
引用本文:刘富东,洪丽蓉,方淳,张蓓蕾,李明华.急性脑梗死动静脉联合与单纯静脉溶栓治疗的疗效观察[J].临床神经病学杂志,2006,19(3):219-220.
作者姓名:刘富东  洪丽蓉  方淳  张蓓蕾  李明华
作者单位:1. 241001,芜湖,皖南医学院附属弋矶山医院神经科
2. 浙江省武警总队杭州医院八病区
3. 上海交大附属第六人民医院放射科
摘    要:目的观察急性脑梗死动静脉联合(IA/IV)与单纯静脉(IV)重组组织型纤溶酶原激活物(rtPA)溶栓治疗的临床疗效。方法对20例急性脑梗死患者分别进行IA/IV(10例)与IV(10例)溶栓治疗,治疗前后分别进行欧洲卒中量表评分(ESS)和Barthel指数(BI)评分,观察其疗效及不良反应。结果IA/IV组患者闭塞段血管均有效再通,其中8例完全再通,2例部分再通;ESS及BI评分均明显高于IV组(均P<0.01),临床总有效率IA/IV组为90%,明显优于IV组的30%(P<0.05)。结论IA/IV溶栓治疗急性脑梗死是一种安全、有效的治疗方法,效果优于IV溶栓治疗。

关 键 词:脑梗死  动静脉结合溶栓  重组组织型纤溶酶原激活物
文章编号:1004-1648(2006)03-0219-02
收稿时间:2005-08-12
修稿时间:2005-09-17

Therapeutic effect observation of combined intra-arterial with intravenous versus single intravenous thrombolysis for patients with acute cerebral infarction
LIU Fu-dong, HONG Li-rong, FANG Chun, et al.Therapeutic effect observation of combined intra-arterial with intravenous versus single intravenous thrombolysis for patients with acute cerebral infarction[J].Journal of Clinical Neurology,2006,19(3):219-220.
Authors:LIU Fu-dong  HONG Li-rong  FANG Chun  
Affiliation:Department of Neurology, the Affiliated Yijishan Hospital of Wannan Medical College, Wuhu 241001, China
Abstract:Objective To analyse the clinical efficacy of combined intra-arterial and intravenous(IA/IV) versus single intravenous(IV) thrombolysis using recombinated tissue plasminogen activator( rt-PA ) for acute cerebral infarction.Methods 20 patients with acute cerebral infarction were treated with IA/IV (10 patients) versus IV (10 patients) thrombolysis using rt-PA. Europe stroke scales (ESS) and Barthel Index (BI) scores were analyzed respectively both before and after the thrombolysis for the 20 patients. Therapeutic effects and adverse effects were observed.Results Total and partial recanalization of the occlusion arteries were showed in 8 and 2 IA/IV patients respectively, and the ESS and BI scores of IA/IV patients were significantly higher than those of IV patients(all P<0.01). Rate of Clinical efficacy of IA/IV was 90% which was better than that of IV group(30%).Conclusions Combined IA/IV thrombolysis may be a safe and effective treatment for acute cerebral infarction, which is more effective than that of single IV thrombolysis.
Keywords:cerebral infarction  combined IA /IV thrombolysis  rt-PA
本文献已被 CNKI 维普 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司    京ICP备09084417号-23

京公网安备 11010802026262号