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1.
Akbil Bengisu Meyer Tim Stubbemann Paula Thibeault Charlotte Staudacher Olga Niemeyer Daniela Jansen Jenny Mühlemann Barbara Doehn Jan Tabeling Christoph Nusshag Christian Hirzel Cédric Sanchez David Sökler Nieters Alexandra Lother Achim Duerschmied Daniel Schallner Nils Lieberum Jan Nikolaus August Dietrich Rieg Siegbert Falcone Valeria Hengel Hartmut Kölsch Uwe Unterwalder Nadine Hübner Ralf-Harto Jones Terry C. Suttorp Norbert Drosten Christian Warnatz Klaus Spinetti Thibaud Schefold Joerg C. Dörner Thomas Sander Leif Erik Corman Victor M. Merle Uta Kurth Florian von Bernuth Horst Meisel Christian Goffinet Christine 《Journal of clinical immunology》2022,42(6):1111-1129
Journal of Clinical Immunology - Six to 19% of critically ill COVID-19 patients display circulating auto-antibodies against type I interferons (IFN-AABs). Here, we establish a clinically applicable... 相似文献
2.
Lu Victor Zhang James Zhou Andrew Krkovic Matija 《European journal of orthopaedic surgery & traumatology : orthopedie traumatologie》2022,32(6):1119-1126
European Journal of Orthopaedic Surgery & Traumatology - The management of limb-length discrepancy secondary to traumatic femoral bone loss poses a unique challenge for surgeons. The Ilizarov... 相似文献
3.
Singh Amita Sun Deyu Mor-Avi Victor Addetia Karima Patel Amit R. DeCara Jeanne M. Ward R. Parker Lang Roberto M. 《The international journal of cardiovascular imaging》2022,38(5):965-974
The International Journal of Cardiovascular Imaging - Echocardiographic evaluation of left ventricular diastolic function relies on a multi-pronged algorithm, which incorporates Doppler-based and... 相似文献
4.
Corrêa Hugo Luca Gadelha André Bonadias Dutra Maurílio Tiradentes Neves Rodrigo Vanerson Passos de Deus Lysleine Alves Moura Sting Ray Gouvêa Silva Victor Lopes Reis Andrea Lucena Honorato Fernando Souza de Araújo Thaís Branquinho de Barros Carolina Fonseca Moraes Milton Rocha Ferreira Carlos Ernesto Santos Prestes Jonato Rosa Thiago Santos 《Sport Sciences for Health》2022,18(2):357-365
Sport Sciences for Health - To investigate the hemodynamic responses, especially HPE following different resistance exercises RE protocols in young adult subjects. Eighty-nine men... 相似文献
5.
Dongbing Lai Emma C. Johnson Sarah Colbert Gayathri Pandey Grace Chan Lance Bauer Meredith W. Francis Victor Hesselbrock Chella Kamarajan John Kramer Weipeng Kuang Sally Kuo Samuel Kuperman Yunlong Liu Vivia McCutcheon Zhiping Pang Martin H. Plawecki Marc Schuckit Jay Tischfield Leah Wetherill Yong Zang Howard J. Edenberg Bernice Porjesz Arpana Agrawal Tatiana Foroud 《Alcoholism, clinical and experimental research》2022,46(3):374-383
6.
Jon C. Tilburt MD David Zahrieh PhD Joel E. Pacyna MA Daniel G. Petereit MD Judith S. Kaur MD Bruce D. Rapkin PhD Robert L. Grubb III MD George J. Chang MD Michael J. Morris MD Evan Z. Kovac MD Kara N. Babaian MD Jeff A. Sloan PhD Ethan M. Basch MD Elizabeth S. Peil MHA Amylou C. Dueck PhD Paul J. Novotny MS Electra D. Paskett PhD Jan C. Buckner MD Daniel D. Joyce MD Victor M. Montori MD Dominick L. Frosch PhD Robert J. Volk PhD Simon P. Kim MD 《Cancer》2022,128(6):1242-1251
7.
Penelas Alice Gonçalves da Silva Eduardo Moreira Fedozzi Julia Mattos Alves Amanda Cypriano Orem Paulo Roberto Barros Poskus Laiza Tatiana Feitosa Victor Pinheiro Guimarães José Guilherme Antunes 《Odontology / the Society of the Nippon Dental University》2022,110(3):569-576
Odontology - This study aimed at evaluating the influence of glass-fiber post (GFP) relining with composites of different opacities on resin cement layer thickness (CLT), bond strength (BS) to root... 相似文献
8.
Mariana Rillo Sato João Augusto Oshiro-Junior Camila Fernanda Rodero Fernanda Isadora Boni Victor Hugo Sousa Araújo Taís Maria Bauab Dean Nicholas John F. Callan Marlus Chorilli 《Journal de Mycologie Médicale》2022,32(4):101296
Introduction and Aim: The indiscriminate use and adverse effects of the main conventional antifungal agents compromise the effectiveness of treating vulvovaginal candidiasis (VVC), mainly caused by the species Candida albicans. This study evaluated the effectiveness of photodynamic therapy (PDT) and the in vitro and in vivo anti-candida potential of the hypericin (HYP)-loaded nanostructured lipid carriers (NLC). Materials and Methods: Empty NLC and NLC-HYP were characterized by the dynamic light scattering technique and transmission electron microscopy to evaluate the average particle size distribution and its morphologies. The in vitro inhibition photodynamic effect of the systems was tested to reduce the planktonic viability of C. albicans. The therapeutic assay photodynamic of the systems was performed to treat VVC in mice. Results: Empty NLC and NLC-HYP presented values of average hydrodynamic diameter, polydispersity index, and ζ-potential from 136 to 133 nm, 0.16 to 0.22, and -18 to -30 mV, respectively, on day 30. Microscopically, the systems showed spherical morphologies and nanoscale particles. Furthermore, in the in vitro inhibition assay, the treatment of PDT with NLC-HYP (NLC-HYP+) showed a significant reduction of the C. albicans planktonic viability compared to YNB negative control after 5 min of LED light irradiation. In the in vivo therapeutic assay, the antifungal group (vaginal antifungal cream) and NLC-HYP+ evaluated in the dark and by PDT, respectively, had a significant log10 reduction in fungal burden compared to the infected group on day 8 of the VVC treatment. Conclusion: Due to the in vitro and in vivo anti-candida potential, PDT-mediated systems can be an effective strategy in VVC therapy. 相似文献
9.
Glutathione S-transferase Polymorphisms in Head and Neck Squamous Cell Carcinoma Treated with Chemotherapy and/or Radiotherapy 下载免费PDF全文
Mauricio Pereira ManigliaAnelise RussoPatrícia Matos Biselli-ChicoteJuliana Garcia de Oliveira-CucoloGabriela Helena Rodrigues-Flemingjosé Victor -ManigliaÉrika Cristina PavarinoEny Maria Goloni-Bertollo 《Asian Pacific journal of cancer prevention》2020,21(6):1637-1644
Background/Aim: The Glutathione S-transferases (GSTs) are important carcinogen-metabolizing enzymes. Polymorphisms involved in these enzymes can modulate the development and treatment of head and neck cancer. To investigate the association of GSTs polymorphisms with head and neck cancer and risk factors, clinical-pathological features, and survival time of the patients treated with chemotherapy and/or radiotherapy. Methods: The GST gene polymorphisms were evaluated in 197 cases and 514 controls by PCR-RFLP-Polymerase Chain Reaction Restriction Fragment Length Polymorphism. Results: The GSTP-313 was associated with a decreased risk for HNSCC (p=0.050). The GSTP1 haplotype analysis revealed a higher frequency of the AC and AT haplotypes in the case group than in the control group (p=0.013 and p=0.019, respectively), and the opposite for G-C haplotype (p = 0.015). Yet, the different combinations between the genotypes were associated with an increased risk of cancer. The study showed no association between the polymorphisms and primary tumor site, clinical-pathological characteristics, treatment (chemotherapy and/or radiotherapy) and survival time of the patients. Conclusion: The GST polymorphisms combination showed an increased risk for carcinogenesis, and studies with larger casuistry can contribute to the clarification of the role in individual patient differences for the response to chemotherapy and/or radiotherapy and identify biomarkers of susceptibility. 相似文献
10.
Lu Victor M. Marek Tomas Gilder Hannah E. Puffer Ross C. Raghunathan Aditya Spinner Robert J. Daniels David J. 《Journal of neuro-oncology》2019,144(3):433-443
Journal of Neuro-Oncology - Multiple studies have reported the loss of trimethylation at lysine (K) 27 on histone 3 (H3K27me3) in high-grade malignant peripheral nerve sheath tumors (MPNSTs).... 相似文献