Association of cardiorespiratory fitness with pressure pain sensitivity and clinical pain in women with fibromyalgia     

Alberto Soriano-Maldonado  Francisco B. Ortega  Diego Munguía-Izquierdo 《Rheumatology international》2015,35(5):899-904

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Acute respiratory distress syndrome in patients with and without diffuse alveolar damage: an autopsy study     

José A. Lorente  Pablo Cardinal-Fernández  Diego Muñoz  Fernando Frutos-Vivar  Arnaud W. Thille  Carlos Jaramillo  Aida Ballén-Barragán  José M. Rodríguez  Oscar Peñuelas  Guillermo Ortiz  José Blanco  Bruno Valle Pinheiro  Nicolás Nin  María del Carmen Marin  Andrés Esteban  Taylor B. Thompson 《Intensive care medicine》2015,41(11):1921-1930

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Drug-resistance in Streptococcus pneumoniae isolates among Spanish middle aged and older adults with community-acquired pneumonia   总被引：1，自引：0，他引：1  

Angel Vila-Corcoles  Ferran Bejarano-Romero  Elisabeth Salsench  Olga Ochoa-Gondar  Cinta de Diego  Frederic Gomez-Bertomeu  Xavier Raga-Luria  Xavier Cliville-Guasch  Victoria Arija 《BMC infectious diseases》2009,9(1):36

Background  

Pneumococcal diseases remain a major cause of morbidity and mortality worldwide. Updated data on drug-resistance from different populations may be important to recognize changes in disease patterns. This study assessed current levels of penicilin resistance among Streptococcus Pneumoniae causing pneumonia in Spanish middle age and older adults.  相似文献   

Large infratentorial subdural hemorrhage diagnosed by ultrasound and MRI in a second-trimester fetus.     

D Paladini  G Sglavo  M Quarantelli  M R D'armiento  P Martinelli  M Salvatore 《Ultrasound in obstetrics & gynecology》2005,26(7):789-91; discussion 791

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Increased factor VIII coagulant activity levels in male carriers of the factor V R2 polymorphism.     

Nicola Martinelli  Domenico Girelli  Paolo Ferraresi  Oliviero Olivieri  Barbara Lunghi  Franco Manzato  Roberto Corrocher  Francesco Bernardi 《Blood coagulation & fibrinolysis》2007,18(2):125-129

A common factor V gene haplotype, the FVR2 haplotype (FVHR2), has been associated with a reduced cofactor activity in activated protein C-mediated activated factor VIII inactivation. Our aim was to investigate the role of FVHR2 as a possible determinant of factor VIII levels in a population study. A total of 516 individuals (401 men, 115 women; mean age 58.4 +/- 10.8 years) were enrolled within the frame of a regional cardiovascular survey, characterized for factor VIII coagulant activity (FVIII:c) and factor V coagulant activity (FV:c) levels, and genotyped for factor V polymorphisms. In men without signs of overt inflammation, FVHR2 carriers had higher levels of FVIII:c than noncarriers (154 IU/dl, 95% confidence interval = 143-166 versus 142 IU/dl, 95% confidence interval = 138-147; P = 0.045) and were more represented in individuals with high (> or = 150 IU/dl) FVIII:c levels (21.2 versus 10.8%; odds ratio = 2.27, 95% confidence interval = 1.17-4.39 after adjustment for age, blood group and high-sensitivity C-reactive protein levels). In conclusion, this clinical report suggests the common FVHR2 as a possible independent determinant of FVIII:c levels. The report concomitantly addresses the relationship between factor V and factor VIII levels and supports the hypothesis of a mild prothrombotic role of FVHR2 by means of increased factor VIII levels.  相似文献   

Compression Neuropathy of the Motor Fibers of the Median Nerve at Wrist Level     

Giacomo Rizzello  Umile Giuseppe Longo  Francesco Franceschi  Nicolò Martinelli  Maria Chiara Meloni  Rodolfo Quadrini  Vincenzo Denaro 《Journal of the Chinese Medical Association》2009,72(5):268-270

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Initial clinical experience with propofol (Diprivan) in repeated boluses and in continuous infusion     

G Martinelli  C Melloni  M G Di Marco  N Franceschelli  E Viganò  L Caporali  R Giuliani  S Isola 《Minerva anestesiologica》1986,52(10):331-337

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Transitional progressive multiple sclerosis: MRI and MTI findings   总被引：1，自引：0，他引：1  

M. Filippi  A. Campi  V. Martinelli  C. Pereira  G. Scotti  G. Comi 《Acta neurologica Scandinavica》1995,92(2):178-182

Transitional progressive multiple sclerosis (MS) is quite an unusual form of presentation and course of the disease. A case with this progressive form is presented and brain MRI and MTI findings are discussed in relation to the possible insight they may provide for understanding the mechanisms that determine progressive disability in MS.  相似文献   

Endoscopic treatment of benign tumors of the nose and paranasal sinuses.   总被引：1，自引：0，他引：1  

Ernesto Pasquini  Vittorio Sciarretta  Giorgio Frank  Cosetta Cantaroni  Giovanni Carlo Modugno  Diego Mazzatenta  Giovanni Farneti 《Otolaryngology--head and neck surgery》2004,131(3):180-186

OBJECTIVE: The endoscopic approach can be successfully employed for the treatment of benign tumors such as fibroosseus and vascular lesions, pleomorphic adenomas, gliomas, and schwannomas. STUDY DESIGN AND SETTING: Nineteen patients diagnosed with benign tumors of the nasal cavity and paranasal sinuses and treated using an endoscopic approach were retrospectively reviewed. The endoscopic approach was used exclusively in 15 cases and was associated with an external approach in 4 cases (due to an intracranial extension of the tumor in 3 patients and its location at the level of the anterior wall of the frontal sinus in the last case). RESULTS: The resection of the lesions was radical in 18 patients and subtotal in 1 case. The mean follow-up was 27 months and only 1 recurrence (5%) was observed in the juvenile angiofibroma group 20 months postoperatively. CONCLUSION: and significance In selected cases, endoscopic surgery can be considered an effective treatment for the resection of benign tumors involving the sinonasal tract.  相似文献   

Actin-free Gc globulin: a rapidly assessed biomarker of organ dysfunction in acute liver failure and cirrhosis.   总被引：2，自引：0，他引：2  

Charalambos G Antoniades  Philip A Berry  Matthew Bruce  Timothy J S Cross  Andrew J Portal  Munther J Hussain  William Bernal  Julia A Wendon  Diego Vergani 《Liver transplantation》2007,13(9):1254-1261

Reductions in serum levels of Gc globulin, a hepatically synthesized component of the extracellular actin scavenger system responsible for complexing circulating actin and attenuating intravascular microthrombus formation, are associated with poor outcome in acute liver failure. Clinically applicable assays of the important actin-free fraction (Af-Gc) have not been available until now. We measured actin-free Gc globulin levels with a novel, rapid assay in 61 cases of acute liver failure (ALF) and in 91 patients with cirrhosis (40 of whom were clinically unstable with extrahepatic organ dysfunction), and studied associations with liver dysfunction, extrahepatic organ dysfunction, indices of disseminated coagulation, and outcome. Reductions in Af-Gc levels mirrored hepatic dysfunction and organ dysfunction in both groups, and discriminated patients with poor prognosis from those with good prognosis in the ALF cohort. Levels were lowest in patients with ALF (10% of control values), but levels were also markedly reduced in both unstable (28%) and stable (44%) patients with cirrhosis. Associations with markers of disseminated intravascular coagulation were seen in both groups, most notably in the cirrhosis cohort, supporting a pathophysiological role for reduced Af-Gc in the evolution of organ dysfunction. In acetaminophen-induced ALF, Af-Gc identified patients with poor prognosis as well as did the Acute Physiology and Chronic Health Evaluation (APACHE II) score (area under the receiver operating characteristic curve, 0.7), and in cirrhosis, Af-Gc was an independent predictor of mortality by multifactorial analysis. In conclusion, the importance of Af-Gc reductions in the development of multiple organ dysfunction in ALF and cirrhosis is highlighted, probably resulting from reduced hepatic production and peripheral exhaustion of this arm of the extracellular actin scavenger system.  相似文献