解郁透达化气法治疗肝郁血结型失眠症105例临床分析   总被引：4，自引：0，他引：4  

黄韬  黄平  戴帅  王翘楚 《上海中医药杂志》2007,41(8):41-42

目的探讨解郁透达化气法治疗肝郁血结所致失眠的临床疗效。方法对105例患者采用解郁透达化气法辨证论治,经2至4周治疗后观察临床疗效。结果105例患者中治愈11例,好转84例,未愈7例,总有效率达90.48%。结论解郁透达化气法治疗肝郁血结的失眠疗效良好。  相似文献   

针刺、耳穴配合耳尖放血治愈顽固性失眠1例     

王燕  陈华德 《中医临床研究》2012,(18):43-43

随着生化节奏的不断加快,各种压力突如其来,失眠成为临床常见疾病。运用针刺、耳穴配合耳尖放血治疗失眠取得良好地疗效。  相似文献   

Polysomnographically determined sleep and body mass index in patients with insomnia     

Lili Huang  Junying Zhou  Yuanfeng Sun  Zhe Li  Fei Lei  Guangyao Zhou  Xiangdong Tang 《Psychiatry research》2013

We assessed associations between polysomnographically determined sleep, especially the amount of slow-wave sleep (SWS), and body mass index (BMI) in patients with insomnia. One hundred and forty-one insomniacs and 55 healthy volunteers completed overnight polysomnographic recordings, and we measured height and body weight. No significant correlations were obtained between total sleep time and BMI among insomniacs. Compared with normal volunteers, insomnia patients exhibited longer sleep latency and shorter total sleep duration. While the two groups had no significant differences in BMI, insomniacs presented with more N1 but less time spend in SWS and rapid eye movement sleep (REMS). Based on their SWS time, we divided insomnia patients into three groups: short (26.99±13.88), intermediate (59.24±8.12), and long (102.21±26.17) SWS groups. The short-SWS group had significantly greater BMI than the long-SWS group. Further analyses with multiple linear regression showed a significant negative correlation between the amount of SWS and BMI scores in insomniacs, whereas no such correlation was found in healthy volunteers after controlling for potential confounds (e.g., age, sex and AHI). Our study suggests that low amounts of SWS may be associated with higher BMI in patients with insomnia.  相似文献   

Sleep disorders and quality of life in renal transplant recipients     

Miklos Zsolt Molnar  Marta Novak  Istvan Mucsi 《International urology and nephrology》2009,41(2):373-382

Kidney transplantation provides the best outcome for patients with end-stage renal failure both in terms of morbidity and mortality and health-related quality of life (QoL). Health-related QoL has become recognized as an important outcome measure in patients with different chronic medical conditions, including chronic kidney disease (CKD). There are several factors in kidney-transplanted patients which have a negative impact on QoL in these patients. Sleep disorders, such as insomnia, sleep apnea syndrome (SAS), and restless legs syndrome (RLS), are common in kidney-transplanted patients and clearly belong to this group of factors, although there is only limited published data available about the association between sleep problems and QoL in this patient population. The prevalence of both insomnia and RLS is reduced in kidney-transplanted patients compared to dialysis patients, and it is similar to the prevalence observed in the general population. The prevalence of sleep apnea, however, is very high, around 30%. The association between the presence of these sleep disorders and impaired QoL has been relatively well documented in dialysis patients, but there is only scarce published information about this association in the kidney transplant population. In this paper, we will summarize data from the literature describing the impact of sleep problems, which are potentially treatable, on QoL in kidney-transplanted patients. We suggest that the appropriate diagnosis and management of sleep disorders may improve QoL in kidney-transplanted patients.  相似文献   

四逆散对失眠大鼠睡眠时相的影响   总被引：3，自引：0，他引：3  

刘珊珊  李廷利  朱维莉 《中国医药导报》2008,5(15):19-20

目的：探讨四逆散对失眠大鼠睡眠时相的影响，为四逆散改善睡眠的作用提供实验依据。方法：采用电刺激诱导大鼠失眠，利用脑电图描记的方法，观察给予四逆散水煎液后失眠大鼠睡眠时相的变化。结果：四逆散水煎液可显著延长失眠大鼠的总睡眠时间（TST），在睡眠时相上主要表现为延长SWS2和REMS，对SWS1没有显著的影响，并使觉醒时间（W）显著减少。结论：四逆散能延长失眠大鼠的SWS2和REMS。  相似文献   

和胃安神方对失眠大鼠血浆及下丘脑食欲素A的影响     

黎发根  李绍旦  杨明会  周建平  曹科  刘毅 《环球中医药》2012,5(11):801-803

目的探讨和胃安神方对失眠大鼠血浆及下丘脑食欲素A（orexin A）的影响。方法将30只雄性wistar大鼠随机分为正常对照组、失眠模型组、和胃安神方中药组。除正常组外,其余两组大鼠均用对氯苯丙氨酸（PCPA）建立大鼠失眠模型。中药组给予和胃安神方水溶液10ml/kg灌胃,其余两组给予等量生理盐水灌胃。6天后处死并取血浆及下丘脑,采用用放射免疫分析法检测血浆及下丘脑组织orexinA的含量。采用单因素方差分析方法进行组间比较。结果和胃安神方中药组血浆orexinA含量为（22.35±4.33）pg/ml,模型组为（29.89±3.04）pg/ml,正常组为（21.28±4.02）pg/ml,中药组显著低于模型组,差异具有统计学意义（P〈0.01）,中药组与正常组比较无显著性差异（P〉0.05）;和胃安神方中药组下丘脑orexinA含量为（21.34±2.94）pg/mg,模型组为（29.75±5.05）pg/mg,正常组为（18.84±3.08）pg/mg,中药组显著低于模型组,差异具有统计学意义（P〈0.01）,中药组与正常组比较无显著性差异（P〉0.05）。结论和胃安神方治疗失眠症的疗效机制可能与其下调orexinA水平有关。  相似文献   

基于子午流注理论浅析补肺汤加味治疗失眠     

赵婧 《中国民族民间医药杂志》2020,(10):90-91

失眠属于睡眠障碍疾病,严重影响患者身心健康、生活质量以及工作状态.子午流注是指气血循行于十二经脉中,并按照十二时辰中阴阳的盛衰变化而呈现出相应的盛衰变化.子午流注与睡眠生理节律相关.基于子午流注理论,笔者应用补肺汤加味治疗丑寅交接之时起病之失眠,方虽精小,却获良效.推而演之,基于子午流注理论治疗不同时辰起病之失眠,可获...  相似文献   

中医辨证施治结合耳穴压豆治疗中风后失眠临床疗效观察   总被引：1，自引：0，他引：1  

邵子杰 《亚太传统医药》2014,(12):85-86

目的：探讨中医辨证施治结合耳穴压豆治疗中风后失眠患者的临床疗效。方法：将中风后失眠患者80例随机分为治疗组和对照组各40例。治疗组采用中药辨证施治结合耳穴（皮质下、交感、内分泌、神门、心、肾、肝、脾等穴位）王不留行籽压法治疗2周;对照组采用西药常用镇静药：地西泮常规口服治疗。采用阿森斯失眠量表进行评分及WHO颁布的失眠临床疗效判断标准等方面判断其疗效。结果：治疗组总有效率为97.5%（39/40）,对照组总有效率为67.5%（27/40）。两组比较治疗组效果明显优于对照组,差异有统计学意义（P〈0.05）。结论：中医辨证施治结合耳穴压豆对中风后失眠患者的临床症状有明显改善作用。其中耳穴压豆具有简便、价廉、无痛、无不良反应等优点,值得临床推广应用。  相似文献   

Insomnia with Short Sleep Duration and Mortality: The Penn State Cohort     

Alexandros N. Vgontzas  Duanping Liao  Slobodanka Pejovic  Susan Calhoun  Maria Karataraki  Maria Basta  Julio Fernández-Mendoza  Edward O. Bixler 《Sleep》2010,33(9):1159-1164

Study Objectives:

Because insomnia with objective short sleep duration is associated with increased morbidity, we examined the effects of this insomnia subtype on all-cause mortality.

Design:

Longitudinal.

Setting:

Sleep laboratory.

Participants:

1,741 men and women randomly selected from Central Pennsylvania.

Measurements:

Participants were studied in the sleep laboratory and were followed-up for 14 years (men) and 10 years (women). “Insomnia” was defined by a complaint of insomnia with duration ≥ 1 year. “Normal sleeping” was defined as absence of insomnia. Polysomnographic sleep duration was classified into two categories: the “normal sleep duration group” subjects who slept ≥ 6 h and the “short sleep duration group” subjects who slept < 6 h. We adjusted for age, race, education, body mass index, smoking, alcohol, depression, sleep disordered breathing, and sampling weight.

Results:

The mortality rate was 21% for men and 5% for women. In men, mortality risk was significantly increased in insomniacs who slept less than 6 hours compared to the “normal sleep duration, no insomnia” group, (OR = 4.00, CI 1.14-13.99) after adjusting for diabetes, hypertension, and other confounders. Furthermore, there was a marginally significant trend (P = 0.15) towards higher mortality risk from insomnia and short sleep in patients with diabetes or hypertension (OR = 7.17, 95% CI 1.41-36.62) than in those without these comorbid conditions (OR = 1.45, 95% CI 0.13-16.14). In women, mortality was not associated with insomnia and short sleep duration.

Conclusions:

Insomnia with objective short sleep duration in men is associated with increased mortality, a risk that has been underestimated.

Citation:

Vgontzas AN; Liao D; Pejovic S; Calhoun S; Karataraki M; Basta M; Fernández-Mendoza J; Bixler EO. Insomnia with short sleep duration and mortality: the Penn State Cohort. SLEEP 2010;33(9):1159-1164.  相似文献   

Healthy Brain Aging: What Has Sleep Got To Do With It?     

Raman K. Malhotra  Abhilash K. Desai 《Clinics in Geriatric Medicine》2010

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