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1.
目的探讨中老年机关干部体质指数(BMI)与其他心血管危险因素聚集的关系。方法选用1 477名机关干部健康体检资料(年龄40~84岁),分析不同BMI组高血压、糖尿病、高胆固醇(TC)、高甘油三酯(TG)和低高密度脂蛋白胆固醇(HDL-C)的聚集情况和相对危险,对危险因素聚集率与BMI进行相关分析。结果男性和女性机关干部其他心血管危险因素的聚集率分别为42.23%、29.21%。随着BMI的增加,其他危险因素的聚集率呈明显升高趋势,男性和女性的危险因素聚集率均与BMI呈直线正相关(r=0.996 5/0.999 2),回归方程^Y=-0.868 5+0.051 0X/-0.848 0+0.045 4X。结论中老年干部心血管病危险因素的聚集率与BMI呈直线正相关。控制超重和肥胖对降低中老年干部心血管病危险因素水平具有非常重要的意义。  相似文献   

2.
目的探讨不同体重指数(BMI)和腰围水平对人群中其他心血管病危险因素聚集的影响.方法将1992~1994年和1998年在我国不同地区中年人群中进行的2次心血管病危险因素调查资料合并共30 561人,比较不同BMI和腰围分组的研究对象其他心血管病危险因素聚集率和聚集的相对危险,其中危险因素聚集定义为同一研究对象具有高血压、高血清总胆固醇、低高密度脂蛋白胆固醇或空腹血糖异常之中的任意2项或2项以上者.结果随着BMI和(或)腰围的增加,人群其他心血管病危险因素的聚集率呈明显上升趋势, 按BMI分层各组中,男女两性腰围与其他心血管病危险因素的聚集率均呈明显的线性上升趋势,同样在不同的腰围分组中,BMI均与其他心血管病危险因素的聚集率呈明显的线性趋势.男性和女性年龄调整心血管病危险因素聚集率在BMI<24 kg/m2、腰围(男/女)<85/80 cm组分别为11.1%和10.4%,BMI<24 kg/m2、腰围(男/女)85~95.9/80~89.9 cm组分别为24.2%和16.9%, BMI 24.0~27.9 kg/m2、腰围(男/女)<85/80 cm组分别为24.0%和17.0%,BMI 24~27.9 kg/m2、腰围(男/女)85~95.9 /80~89.9 cm组分别为34.3%和24.0%. BMI 24.0~27.9 kg/m2、腰围(男/女)≥95/90 cm组分别为40.8%和29.6%,BMI≥28 kg/m2、腰围(男/女)85~95.9/80~89.9 cm组分别为44.2%和29.9%,BMI≥28 kg/m2、腰围(男/女)≥95/90 cm组分别为54.7%和35.4%.结论 BMI和腰围水平均与其他心血管病危险因素的聚集有独立的正相关性.保持BMI和腰围均在正常范围对心血管健康是很重要的.  相似文献   

3.
北京市中老年人体质指数与死亡的关系   总被引:1,自引:0,他引:1  
目的:探讨北京市中老年人体质指数(BMI)与死亡的关系,方法:采用前瞻队列研究方法,于1991年对北京市40岁以上的自然人群共6209人进行基线危险因素调查后,并随访至1999年12月,对在随访期间发生的所有死亡病例按ICD-9编码进行登记,并在个体水平对BMI与总死亡及几种主要死因的关系进行分析。结果:近10年北京市中老年人前5位主要死因依次为心脑血管疾病,肺心病,消化道肿瘤,不明原因突然死亡,肺癌,其死亡构成比分别为33.3%,13.8%,11.2%,7.4%,5.6%,人群总死亡率及不吸烟者总死亡率均以BMI值23.6-26.2组最小,以此BMI组为参照,BMI<21.2组上述二组人群总死亡的RR值分别为1.7和1.9,在BMI≥26.2组以上二组人群总死亡的RR值分别为1.3和1.5,BMI与心血管病死亡呈正关联,BMI≥26.2组较BMI<21.2组心血管病死亡的RR值为1.2,BMI与肺心病,消化道肿瘤,肺癌,肺炎及不明原因突然死亡分别均呈U型关系,均以BMI值23.6-26.2组死亡率最低,与此BMI组相比,BMI<21.2组因上述5种疾病死亡的RR值分别为14.8,1.1,5.6,2.4和2.6,BMI≥26.2组因上述5种疾病死亡的RR值分别为3.0,1.9,3.7,2.2和1.5,各BMI组均以心血管病死亡构成比最大(28.0%-54.8%),结论:北京市中老年人体质指数与总死亡呈U型关系;心脑血管疾病仍是目前影响人们健康的最主要疾病,其死亡危险性随BMI的增加而增加。  相似文献   

4.
体质指数与非吸烟女性肺癌关系的病例对照研究   总被引:16,自引:0,他引:16  
研究分析体质指数与非吸烟女性肺癌的关系。方法1992年2月至1993年12月,上海地区开展的一项大规模女性肺癌人群基础上的病例对照研究,共调查了非吸烟女性肺癌病例504例及人群对照601例。  相似文献   

5.
OBJECTIVE: Although there is a clear positive association between obesity and the incidence and severity of cardiovascular disease, the association between underweight and cardiovascular disease is unclear. The objective of this study was to examine the relation between body mass index (BMI) and cardiovascular disease in Japan, where the proportion of the population that is underweight is relatively high. METHOD: A total of 43,916 Japanese adults (21,003 men and 22,913 women) aged 40 to 79 years who had no history of cancer, ischemic heart disease (IHD), or stroke participated in the baseline survey in 1994. Hazard ratios (HR) and their 95% confidence intervals (CIs) for death due to total cardiovascular disease, all strokes, ischemic stroke, hemorrhagic stroke, and IHD were calculated according to BMI by using Cox's proportional hazards regression models. The 22.5-24.9 kg/m(2) BMI category was used as the reference category in all analyses. RESULTS: There were U-shaped associations between BMI and total cardiovascular disease, all stroke, hemorrhagic stroke, and IHD mortality, and a J-shaped association between BMI and ischemic stroke mortality. Participants with a BMI <18.5 kg/m(2) had a significantly increased risk of total cardiovascular disease, all stroke, hemorrhagic stroke, and IHD mortality, and the multivariate HR (95% CI) was 1.62 (1.19-2.19), 1.50 (1.02-2.21), 2.11 (1.07-4.17), 1.83 (1.11-3.01), respectively. CONCLUSION: Underweight was substantially associated with hemorrhagic stroke and IHD mortality in Japan, while obesity was associated with increased risk of total cardiovascular disease mortality and mortality from individual cardiovascular diseases.  相似文献   

6.
腰围和体质指数动态变化对高血压发病的影响   总被引:2,自引:0,他引:2  
Luo WS  Guo ZR  Hu XS  Zhou ZY  Wu M  Zhang LJ  Liu JC 《中华预防医学杂志》2011,45(11):1012-1016
目的 探讨腰围(WC)和BMI在2年随访时间内的动态变化对队列人群高血压发病的影响.方法 采用前瞻性研究方法,于2002年1月,对江苏省多代谢异常和代谢综合征(MS)综合防治研究队列人群中随访时间满2年的5888名对象进行第1次随访,完成随访4582名,并于2006年3月对随访时间满5年及参与了第1次随访的对象进行了第2次随访,完成2次随访的对象共3847名,其中满足条件的共2778名基线血压正常对象被纳入分析.基线时WC或BMI正常者在第1次随访时变为非正常者以及基线WC或BMI不正常者在第1次随访时依旧不正常者定义为非控制组;基线WC或BMI非正常者在第1次随访时变为正常以及基线WC或BMI正常者在第1次随访时依旧保持正常者定义为控制组.以第2次随访时是否为高血压作为结局变量(高血压=1,正常血压=0).运用COX比例风险回归模型分析相互调整的WC和BMI差值与高血压发病的关系,以及按照WC和BMI控制与否分层的高血压发病风险,并计算相应的OR和RR值及95% CI值.结果 2778名研究对象中,新发高血压660例.WC差值和BMI差值以连续型变量进入模型作相巨调整时,男女性中高血压发病与WC差值的关联仍具有统计学意义(男性:OR=1.04,95% CI:1.01~1.05;女性:OR=1.04,95%CI:1.02 ~1.06),而与BMI差值的关联不再具有统计学意义(男性:OR=1.04,95%CI:0.97~1.11;女性:OR =0.98,95% CI:0.93~1.03).不论基线WC正常与否,非控制组人群的高血压风险高于控制组人群(基线WC正常组:RR=1.41,95% CI:1.01~2.39;基线WC非正常组:RR =4.41,95% CI:1.66 ~9.80).而在基线BMI非正常组中,控制组与非控制组的高血压发病风险差异无统计学意义(RR=1.33,95% CI:0.88 ~2.02).当WC得到控制,BM1控制与否对高血压发病风险无明显影响(男性:RR=1.03,95% CI:0.36~2.96;女性:RR =1.02,95% CI:0.70~5.85),WC未得到控制时,即使BMI得到控制,高血压发病风险仍会明显增加(男性:RR =4.03,95% CI:1.61~10.09;女性:RR=1.55,95% CI:1.13 ~3.60).结论 WC和BMI的控制均可降低高血压发病风险,而相比于控制BMI,控制WC对降低高血压风险的效果更好.  相似文献   

7.
8.
To compare the effect of potentially modifiable lifestyle factors on the incidence of vascular disease in women with and without diabetes. In 1996–2001 over one million middle-aged women in the UK joined a prospective study, providing medical history, lifestyle and socio-demographic information. All participants were followed for hospital admissions and deaths using electronic record-linkage. Adjusted relative risks (RRs) and incidence rates were calculated to compare the incidence of coronary heart disease and stroke in women with and without diabetes and by lifestyle factors. At recruitment 25,915 women (2.1% of 1,242,338) reported current treatment for diabetes. During a mean follow-up of 6.1 years per woman, 21,928 had a first hospital admission or death from coronary heart disease (RR for women with versus without diabetes = 3.30, 95% CI 3.14–3.47) and 7,087 had a first stroke (RR = 2.47, 95% CI 2.24–2.74). Adjusted incidence rates of these conditions in women with diabetes increased with duration of diabetes, obesity, inactivity and smoking. The 5-year adjusted incidence rates for cardiovascular disease were 4.6 (95% CI 4.4–4.9) per 100 women aged 50–69 in non-smokers with diabetes, 5.9 (95% CI 4.6–7.6) in smokers with diabetes not using insulin and 11.0 (95% CI 8.3–14.7) in smokers with diabetes using insulin. Non-smoking women with diabetes who were not overweight or inactive still had threefold increased rate for coronary disease or stroke compared with women without diabetes. Of the modifiable factors examined in middle aged women with diabetes, smoking causes the greatest increase in cardiovascular disease, especially in those with insulin treated diabetes.  相似文献   

9.
目的 分析北京广外社区55岁以上居民踝臂血压指数变化与心血管病相关危险因素关系.方法 选取2014-2015年“十二五”国家科技支撑计划项目广外社区协作组55岁以上361例人群资料,通过问卷调查了解人群基本情况、家族史、生活方式及行为相关危险因素;体格检查收集调查对象的身高、体重、腰围、血压,踝臂血压、身体脂肪率,利用SPSS 19.0软件包进行统计分析.结果 ①调查人群踝臂血压指数(ABI)均值为(1.22±0.11),其中男性水平(1.26±0.11)和女性ABI值(1.21±0.11)之间差异无统计学意义(P =0.306);②方差分析比较各年龄组之间ABI值的差异显著(P<0.05);③高血压组ABI值(1.21±0.10)与非高血压组ABI值(1.24±0.11)相比,两组差异具有统计学意义(P =0.033).对生活方式和行为、家族史等因素进行Logistic回归分析得出:BMI、年龄、身体脂肪率、高血压家族史是影响ABI变化的主要影响因素.结论 随着年龄增长,ABI值逐渐下降,高血压、年龄、体质指数、身体脂肪率和家族高血压病史是踝臂血压指数异常的重要影响因素.通过对踝臂指数的监测,可以有针对性开展高危人群心血管疾病早期评估和干预.  相似文献   

10.
OBJECTIVE: To estimate effects of weight change on incidence of major cardiovascular events in the Italian population-based Progetto CUORE. METHODS: Prospective observation in 12 Italian population-based cohorts on etiology of cardiovascular disease. Twenty-thousand six-hundred-forty-seven men and women aged 35-69 years without previous CVD, examined at baseline between 1984 and 1993 and followed for median time 8.5 years, with validated first cardiovascular events. Standardised anthropometric variables, lifestyle and biochemical risk factors for CVD; major cardiovascular events as end-points. RESULTS: Linear regression between BMI and major CVD risk factors was combined with Cox coefficients from a prediction model of CVD, CHD and stroke using major risk factors as dependent variables. Estimated cardiovascular risk reductions with BMI lowered by 1 to 3 U were: for men 3.8% to 10.9% for all cardiovascular events, 4.2% to 12.1% for CHD, and 2.3% to 6.9% for stroke; for women 2.8% to 8.1% for all cardiovascular events, 3.4% to 9.8% for CHD, and 2.1% to 6.2% for stroke. CONCLUSIONS: Body weight level influences cardiovascular disease risk in the Italian population.  相似文献   

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